Designed to replenish the body's essential enzymes and probiotics.
Formulated with DigeZyme® and LactoSpore®.
100mg
of key digestive enzymes per serving
150
million live bacteria per serving
DigeZyme® supplements the gastrointestinal tract with enzymes to adequately support the body’s ability to digest food. LactoSpore® can help maintain the proper balance between healthy bacteria (probiotics) and potentially unhealthy bacteria in the digestive tract.

DigeZyme®: Utilise the Complete Spectrum of Nutrients in Your Food.
Digestive enzymes are special catalytic proteins that help your body break down foods to utilise their complete spectrum of nutrients. DigeZyme® provides natural plant enzymes that are not inactivated by stomach acid, meaning optimal nutrient release.

Product Classification

Gluten-Free

Good Manufacturing Practices

Isotonic

No Detectable GMO

Vegan
How to Take

Step 1
Pour 1 level, white bottle capful of powder into the overcap.

Step 2
Add water to the line on the overcap (2 fl oz/60 mL) and stir.

Step 3
Enjoy with or immediately following a meal. Additional servings may be taken if necessary.
Key Ingredients & Benefits

DigeZyme®
supports the breakdown of complex macromolecules into energy sources
promotes the release of the nutrient content from the foods we eat
supplements the gastrointestinal tract with enzymes to adequately support the body’s ability to digest food

Bacillus Coagulans (LactoSpore®)
prevents growth of putrefactive microorganisms responsible for ill health
delivers an effective strain of helpful bacteria
Isotonix Digestive Enzymes Advantage
Isotonix® Digestive Enzymes with Probiotics is an isotonic capable food supplement that offers a unique blend of enzymes and probiotics, that help maintain healthy cholesterol levels as well as promote digestion and the absorption of nutrients.
Isotonix Delivery System

:05 Minutes
Isotonix Liquid Vitamins
- Formulated to survive digestion.
- Delivers concentrated nutrients to the site of absorption.
- Contains no fillers or binders.
- No artificial colour or flavours.

:40 Minutes
Standard Vitamin Tablet
- Contains lab-created coatings and lubricants.
- Often contains artificial colours, nutrients and flavours.
- Limited absorption of nutrient utilisation.
Frequently Asked Questions
What sets Isotonix® Digestive Enzymes with Probiotics apart?
Isotonix Digestive Enzymes with Probiotics is more than an occasional digestion aid; it utilises a formula of patented ingredients — including DigeZyme®, an effective probiotic enzyme blend, and Lactospore®, a special probiotics strain — that replenish essential digestive enzymes and probiotics for your health. In addition, Isotonix Digestive Enzymes with Probiotics is formulated using the revolutionary Isotonix delivery system. It’s a lemon flavoured, easy-to-take, and once-a-day supplement both children and adults will enjoy. For adults, one serving supplies more than 100 mg of key digestive enzymes and 150 million live bacteria.
What happens when we eat?
Even before we eat our bodies’ digestive action begins to take place. Simply smelling food activates our salivary glands (hence, the term, "mouth watering"). As food enters the stomach, the stomach acid and pepsin work together to begin breaking the food down into material the small intestine (where most nutrients are absorbed) can use. Enzymes specific to each of the three nutrient groups are released at this stage, further breaking down the food and contributing to the digestive and absorption processes. These processes continue into the large intestine until the food’s nutritional content is extracted by the body.
What is DigeZyme®?
DigeZyme® is a multienzyme complex composed mainly of amylases (which digest starches), proteases (which digest proteins) and lipases (which digest fats). These digestive enzymes collectively support the breakdown of complex macromolecules into energy sources and promote the release of the nutrient content from the foods we eat. The digestive system naturally produces digestive enzymes. DigeZyme supplements the gastrointestinal tract with enzymes to adequately support the body’s ability to digest food. In addition to the amylases, proteases, and lipases, DigeZyme contains two additional digestive enzymes including lactase (which digests lactose from dairy products) and cellulase (which digests cellulose fibres). The enzymes in this complex are of microbial origin (fungal amylase, lipase, lactase, cellulase; and a bacterial neutral protease). The product is, therefore, entirely of non-animal origin.
Why are digestive enzymes important for my and my child’s health?
Proper digestion is essential for the body to effectively utilise food for use by cells and tissues. Enzymes support the normal breakdown of food into substances that can be used to provide energy to the body. Supplementation with digestive enzymes provides the body with the additional support it needs for proper digestion.
What are probiotics?
Probiotics are beneficial organisms that promote a healthy intestinal tract environment. Probiotics can help support the body in maintaining proper digestive functions and improving emotional health. Bacillus coagulans bacteria reside mostly in the large intestine and help break down undigested food. These "friendly" bacteria can help the absorption of vitamins and minerals and can actually synthesise some vitamins, such as biotin and vitamin K. In addition, these beneficial bacteria contribute to the breaking down of fibres and undigested starch into simple sugars. These simple sugars then function as fuel for the cells that line the large intestine.
What are the "good" bacteria?
All bacteria are not harmful. In fact, if it weren’t for "good" bacteria, we would be unable to digest food. Many people, especially women, know the importance of having "good" bacteria in their system, and many actually take supplements like Lactobacillus acidophilus to keep healthy. Isotonix Digestive Enzyme Formula with Probiotics contains probiotic bacteria called Bacillus coagulans, which was designed to help replenish the "good" bacteria that can be harmed by things like the ingestion of chlorinated water and antibiotics. These "friendly" bacteria help to repopulate the colon, displacing harmful bacteria, and promote an appropriate pH balance.
When is the best time to take Isotonix Digestive Enzymes?
It is generally recommended that enzyme supplements be taken at the beginning of or early in the meal to assure appropriate digestive support, since most food stays in the upper part of the stomach for an hour and half. However, if the enzymes are not taken before or at the beginning of the meal, they can be supplemented after the meal.
Are there any allergen warnings for Isotonix Digestive Enzymes?
Isotonix Digestive Enzymes is a vegetarian product and contains no added wheat, soy, yeast, gluten, artificial flavour, starch, salt, preservatives or milk.
Research Scope
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- Anthony H, Collins CE, Davidson G, et al. Pancreatic enzyme replacement therapy in cystic fibrosis: Australian guidelines. J Pediatr—Child Health. 1999; 35:125-129.
- Barrett A.J., Rawlings ND, Woessner JF. The Handbook of Proteolytic Enzymes, 2nd ed. Academic Press, 2003. ISBN 0120796104.
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- Bock U, Kolac C, Borchard G, et al. Transport of proteolytic enzymes across Caco-2 cell monolayers. Pharm Res. 1998; 15:1393-1400.
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- Carriere, F., C. Withers-Martinez, H. van Tilbeurgh, A. Roussel, C. Cambillau, and R. Verger. 1998. Structural basis for the substrate selectivity of pancreatic lipases and some related proteins. Biochim Biophys Acta 1376:417-32.
- Chapin III, F.S., P.A. Matson, H.A. Mooney. Principles of Terrestrial Ecosystem Ecology. Springer-Verlag New York, NY. 2002
- Coenen TMM, Bertens AMC, De Hoog SCM, Verspeek-Rip CM. Safety evaluation of a lactase enzyme preparation derived from Kluyveromyces lactis. Food Chem Toxicol. 2000; 38:671-677.
- de Smet PA, Pegt GW, Meyboom RH. [Acute circulatory shock following administration of the non-regular enzyme preparation Wobe-Mugos]. [Article in Dutch]. Ned Tijdschr Geneeskd. 1991; 135:2341-2344.
- Diaz, B. L., and J. P. Arm. 2003. Phospholipase A(2). Prostaglandins Leukot Essent Fatty Acids 69:87-97.
- Dominguez-Munoz JE, Birckelbach U, Glassbrenner B, et al. Effect of oral pancreatic enzyme administration on digestive function in healthy subjects: comparison between two enzyme preparations. Aliment Pharmacol Ther. 1997; 11:403-408.
- Eckert K, Grabowska E, Stange R, et al. Effects of oral bromelain administration on the impaired immunocytotoxicity of mononuclear cells from mammary tumor patients. Oncol Rep. 1999; 6:1191-1199.
- Egmond, M. R., and C. J. van Bemmel. 1997. Impact of Structural Information on Understanding of Lipolytic Function, p. 119-129, Methods Enzymol vol. 284.
- Farkas G, Takacs T, Baradnay G, Szasz Z. [Effect of pancreatin replacement on pancreatic function in the postoperative period after pancreatic surgery]. [Article in Hungarian]. Orv Hetil. 1999; 140:2751-2754.
- Gilbert B, Rouis M, Griglio S, de Lumley L, Laplaud P. 2001. Lipoprotein lipase (LPL) deficiency: a new patient homozygote for the preponderant mutation Gly188Glu in the human LPL gene and review of reported mutations: 75 % are clustered in exons 5 and 6. Ann Genet 44(1):25-32.
- Girod, A., C. E. Wobus, Z. Zadori, M. Ried, K. Leike, P. Tijssen, J. A. Kleinschmidt, and M. Hallek. 2002. The VP1 capsid protein of adeno-associated virus type 2 is carrying a phospholipase A2 domain required for virus infectivity. J Gen Virol 83:973-8.
- Goni FM, Alonso A. 2002 Sphingomyelinases: enzymology and membrane activity. FEBS Lett. 531(1):38-46.
- Greenberger NJ. Enzymatic therapy in patients with chronic pancreatitis. Gastrenterol Clin North Am. 1999; 28:687-693.
- Hedstrom L. Serine Protease Mechanism and Specificity. Chem Rev 2002;102:4501-4523.
- Heikinheimo, P., A. Goldman, C. Jeffries, and D. L. Ollis. 1999. Of barn owls and bankers: a lush variety of alpha/beta hydrolases. Structure Fold Des 7:R141-6.
- Hooper NM. Proteases in Biology and Medicine. London: Portland Press, 2002. ISBN 1855781476.
- Identification of a variant associated with adult-type hypolactasia. Nat Genet 2002;30: 233-7. Free text. PMID 11788828.
- Kaul R, Mishra BK, Sutrador P, et al. The role of Wobe-Mugos in reducing acute sequelae of radiation in head and neck cancers—a clinical phase-III randomized trial. Indian J Cancer. 1999; 36:141-148.
- Kiessling WR. [Anaphylactic reaction in enzyme therapy of multiple sclerosis]. [Article in German]. Fortschr Neurol Psychiatr. 1987; 55:385-386.
- Klein G, Kullich W. [Reducing pain by oral enzyme therapy in rheumatic diseases]. [Article in German]. Wien Med Wochenschr. 1999; 149:577-580.
- Lowe, M. E. 1992. The catalytic site residues and interfacial binding of human pancreatic lipase. J Biol Chem 267:17069-73.
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- Puente XS, Lopez-Otin C. A Genomic Analysis of Rat Proteases and Protease Inhibitors. Genome Biol 2004;14:609-622.
- Puente XS, Sanchez LM, Overall CM, Lopez-Otin C. Human and Mouse Proteases: a Comparative Genomic Approach. Nat Rev Genet 2003;4:544-558.
- Retrieved from " http://www.lactospore.com/intro.htm"
- Retrieved from "http://en.wikipedia.org/wiki/Lactase"
- Retrieved from "http://en.wikipedia.org/wiki/Lipase"
- Retrieved from "http://en.wikipedia.org/wiki/Sucrase"
- Ross J, Jiang H, Kanost MR, Wang Y. Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships. Gene 2003;304:117-31.
- Rowan AD, Buttle DJ, Barrett AJ. The cysteine proteinases of the pineapple plant. Biochem J. 1990; 266:869-875.
- Schrag, J. D., and M. Cygler. 1997. Lipases and alpha/beta hydrolase fold. Methods Enzymol 284:85-107.
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- Solomon, Eldra P.; Berg, Linda R.; & Martin, Diana W. (2002). Biology (6th ed). Tho
- Spiegel, S., D. Foster, and R. Kolesnick. 1996. Signal transduction through lipid second messengers. Curr Opin Cell Biol 8:159-67.
- Stauder G, Ransberger K, Streichhan P, et al. The use of hydrolytic enzymes as adjuvant therapy in AIDS/ARC/LAS patients. Biomed Pharmacother. 1988; 42:31-34.
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- Svendsen, A. 2000. Lipase protein engineering. Biochim Biophys Acta 1543:223-238.
- The Merck Manual of Diagnosis and Therapy, Chapter 24
- Tjoelker, L. W., C. Eberhardt, J. Unger, H. L. Trong, G. A. Zimmerman, T. M. McIntyre, D. M. Stafforini, S. M. Prescott, and P. W. Gray. 1995. Plasma platelet-activating factor acetylhydrolase is a secreted phospholipase A2 with a catalytic triad. J Biol Chem 270:25481-7.
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- Wald M, Závadová E, Pouková P, et al. Polyenzyme preparation Wobe-Mugos inhibits growth of solid tumors and development of experimental metastases in mice. Life Sciences. 1998; 62:PL43-48.
- Winkler, F. K., A. D'Arcy, and W. Hunziker. 1990. Structure of human pancreatic lipase. Nature 343:771-4.
- Withers-Martinez, C., F. Carriere, R. Verger, D. Bourgeois, and C. Cambillau. 1996. A pancreatic lipase with a phospholipase A1 activity: crystal structure of a chimeric pancreatic lipase-related protein 2 from guinea pig. Structure 4:1363-74.
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Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle.
*DigeZyme® and LactoSpore® are registered trademarks of the Sabinsa Corporation.
Reviews
Customer Rating
5.0 out of 5 star rating.
(5 reviews)
would recommend this product.
- Newest
- Highest Rating
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- Most Helpful
This product saved my life, fast acting and super easy to take. I suffer with acid reflux and it’s extremely painful when it occurs but taking this not only gets to it straight away it actually reduces the amount of attacks I now have. Highly recommend and the ingredients are spot on. No unnecessary ingredients like in some others I looked at and ingredients in there that actually help other mechanisms in the body. 10 out of 10 for me!!!!
Response from Customer Service on 22/10/2019
Dear Mr. Patterson,
We received your product review of the Isotonix Digestive Enzymes and wanted to reach out with our thanks! We are so pleased to hear you are enjoying this product and are experiencing the many benefits that have helped ease the pain and reduced your attacks.
Kind Regards
SHOP.COM
Amazing Product
by NATALIAR
on 25/6/2019
This is amazing! It saved my life. I don't have bloated stomach anymore. It helps me with my health and wellbeing. Everyone should have this. And it taste great. Highly recommended.
Will never go a day without!
by REBECCAM
Shop Consultant
on 11/6/2019
I will never be without this product. It’s not just changed my life but my son and my mum too. I used to constantly be bloated before I started taking digestive enzymes. I don’t get that feeling now and if I do after certain food, I take it straight away. Love the taste and love how good it is for my gut health.
Always in my bag
by Anonymous
on 18/2/2019
loving this product, very effective. after food poisoning,I just taken it, in about 15 min the symptoms of stomach pain slow down, I were noticeably better.
Love this product!!!
by ROOPALP
on 2/4/2018
One of my favourite products!! I recently had an IBS episode and the digestive enzymes helped me and I felt better quicker than usual. I would recommend this product to everyone!
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