- Contributes to normal function of bones, teeth, cartilage, gums, skin and blood vessels
- Contributes to healthy inflammatory response
- Contributes to normal absorption and utilisation of calcium and phosphorous
- Contributes to normal blood calcium concentrations
- Contributes to the maintenance of normal muscle function and neurotransmission
- Contributes to normal blood clotting
- Contributes to maintenance of normal vision
- Contributes to maintenance of normal skin and mucous membranes
- Contributes to protection of cells from oxidative damage
- Contributes to normal collagen formation
- Contributes to normal function of the immune and nervous system
- Contributes to normal energy metabolism
- May contribute to reduction of fatigue
- Contributes to normal psychological functions
- Contributes to regeneration of vitamin E
- Contributes to the normal metabolism of iron in the body
- Contributes to the maintenance of normal red blood cells
- Contributes to normal cell division and differentiation
- Contributes to normal function of digestive enzymes
- Contributes to electrolyte balance
- Contributes to normal protein synthesis
- Helps maintain normal blood pressure
- If taken as directed, daily intake provides 750 mg of calcium, the equivalent of a 20 fl. oz. glass of milk
- This intake also provides 25 mcg of vitamin D to assist with calcium absorption and utilisation
Ordinary calcium tablets require stomach acid to dissolve its compounds. Calcium in tablet form is difficult for your body to absorb. People may fail to absorb tablet calcium supplements because the calcium supplement is not blended with Vitamin D and magnesium; these are necessary to aid in the absorption and use of calcium. Even if the calcium tablet is blended correctly, it may be difficult for the body to utilise or break down the calcium. One explanation may be that many calcium brands use calcium from eggshell or oyster shell, which may not be well-absorbed by the body. Calcium absorption may also be disrupted by DCP, a binding agent used to hold the tablet together. DCP does not break down in the body. In addition to binders, some calcium supplements may have additives such as chlorine and other chemicals. Even assuming no binders are used in the calcium tablet, the body must still break down a hard-pressed tablet into a usable form. If the tablet cannot be broken down sufficiently in the stomach, then the calcium will not be absorbed. If you can't break down the calcium, your body is robbed of the calcium needed to support bodily functions.
Isotonix Calcium Plus is an isotonic-capable food supplement made with a combination of calcium (as carbonate, lactate, phosphate, sulphate and citrate), magnesium, beta-carotene, riboflavin and vitamins c and D3, needed for the maintenance of normal bones and teeth. Isotonix Calcium Plus delivers an efficient calcium solution in a natural lemon-lime flavour. Many calcium supplements exist in the marketplace, but only Isotonix Calcium Plus delivers a potent package of calcium and complementary nutrients through an isotonic system of delivery. This translates into a lower cost overall when compared to calcium supplements in pill form by making more of the active ingredients available to the body. Don't be misled by ingredient amounts. What really counts is the amount of active ingredients that your body can ultimately use.
Isotonic, which means “same pressure,” bears the same chemical resemblance of the body’s blood, plasma and tears. All fluids in the body have a certain concentration, referred to as osmotic pressure. The body’s common osmotic pressure, which is isotonic, allows a consistent maintenance of body tissues. In order for a substance to be absorbed and used in the body’s metabolism, it must be transported in an isotonic state.
Isotonix food supplements are delivered in an isotonic solution. This means that the body has less work to do to in obtaining maximum absorption. The isotonic state of the suspension allows nutrients to pass directly into the small intestine and be rapidly absorbed into the bloodstream. With Isotonix products, little nutritive value is lost, making the absorption of nutrients highly efficient while delivering maximum results.
The highest concentration of calcium is found in milk. Other foods rich in calcium include vegetables such as collard greens, Chinese cabbage, mustard greens, broccoli, bok choy and tofu. Calcium is an essential mineral with a wide range of biological roles. Calcium accounts for approximately 40 percent of bone weight. The skeleton has a structural requisite and acts as a storehouse for calcium. Apart from being needed for the maintenance of normal bones and teeth, calcium contributes to normal muscle function and neurotransmission. Calcium also contributes to normal blood clotting and normal energy metabolism. It contributes to normal cell division and differentiation. Calcium also contributes to normal function of digestive enzymes.
Sufficient daily calcium intake is necessary for maintaining optimal bone density and healthy bones and teeth. Calcium deficiency has been associated with poor cardiovascular health, poor colon health and poor muscular function. When the body doesn’t get enough calcium per day, it draws calcium from your bones possibly resulting in Osteoporosis. Osteoporosis is an age-related thinning of the bones, which may lead to a higher risk of broken hips, ribs, pelvis, weakened bones and stooped posture which comes from an accumulation of small fractures in the vertebrae. Bones become brittle with age, but calcium rich diet combined with some exercise can go a long way keep bones strong.
Foods rich in magnesium include unpolished grains, nuts and green vegetables. Green leafy vegetables are potent sources of magnesium because of their chlorophyll content. Meats, starches, dairy products and refined and processed foods contain low amounts of magnesium. Recent research shows that many people’s diets are deficient in magnesium.
Magnesium is a component of the mineralised part of bone and supports the normal metabolism of potassium and calcium in adults. It helps maintain normal levels of potassium, phosphorus, calcium, adrenaline and insulin. It also supports the normal transport of calcium inside the cell for utilisation. Magnesium promotes the normal functioning of muscle and nervous tissue and the normal synthesis of all proteins, nucleic acids, nucleotides, cyclic adenosine monophosphate, lipids and carbohydrates. Magnesium helps combat oxidative stress and lipid peroxidation.
Magnesium supports normal energy release, regulation of the body temperature, nerve function, adaptation to stress and metabolism. Importantly, magnesium also supports the body’s ability to build healthy bones and teeth and develop muscles. It works together with calcium and vitamin D to help keep bones strong. Magnesium, when combined with calcium, helps support the heart muscle, helps maintain a regular heartbeat and helps maintain normal blood pressure.
Manganese is a mineral found in large quantities in both plant and animal matter. The most valuable dietary sources of manganese include whole grains, nuts, leafy vegetables and teas. Manganese is concentrated in the bran of grains, which is often removed during processing.
Only trace amounts of this element can be found in human tissue. Manganese is predominantly stored in the bones, liver, kidney and pancreas. It contributes to the maintenance of normal bone and to the normal formation of connective tissue. Manganese also contributes to normal energy-yielding metabolism.
Manganese is a component of the antioxidant enzyme manganese superoxide dismutase (MnSOD). Antioxidants scavenge free radicals that can cause premature aging and oxidative stress to the body. These particles occur naturally in the body but can damage cell membranes, interact with genetic material and possibly contribute to the ageing process. Antioxidants such as MnSOD contribute to the protection of cell constituents from oxidative damage.
Vitamin B2 (Riboflavin-5-Phosphate)
Vitamin B2 is found in liver, dairy products, dark green vegetables and some types of seafood. Vitamin B2 serves as a coenzyme, working with other B vitamins. Vitamin B2 plays a crucial role in turning food into energy as a part of the electron transport chain, driving cellular energy on the micro-level. Vitamin B2 is water-soluble and cannot be stored by the body except in insignificant amounts. It must be replenished daily.
Riboflavin contributes to the normal metabolism of iron in the body, the maintenance of normal red blood cells and the normal function of the nervous system. It contributes to the maintenance of normal skin and mucous membranes, normal vision and contributes to the protection of cell constituents from oxidative damage. Riboflavin contributes to the reduction of tiredness and fatigue, and contributes to normal energy metabolism.
Vitamin C (Ascorbic Acid)
The best food sources of vitamin C include all citrus fruits (oranges, grapefruit, lemons and tangerines), strawberries, tomatoes, broccoli, Brussels sprouts, peppers and cantaloupe. Vitamin C is a "fragile" vitamin and can be easily destroyed by cooking or exposure of food to oxygen.
Vitamin C contributes to the protection of cell constituents from oxidative damage, in addition to increasing iron absorption. Vitamin C contributes to normal collagen formation and the normal function of bones, teeth, cartilage, gums, skin and blood vessels. Vitamin C contributes to the normal function of both the immune and nervous systems. Vitamin C contributes to normal energy-yielding metabolism and it may contribute to the reduction of tiredness and fatigue. Vitamin C contributes to the regeneration of the reduced form of Vitamin E, and it also contributes to normal psychological functions.
Vitamin C has become the world's most popular vitamin. The most convincing evidence suggesting the need for vitamin C supplementation is based on the fact that humans are incapable of producing vitamin C in their bodies.
Vitamin D3 (Cholecalciferol)
Regular sunlight exposure is the main way that most humans get their vitamin D. Food sources of vitamin D include vitamin D-fortified milk (2.5 mcg per cup), cod liver oil, and fatty fish such as salmon. Small amounts of vitamin D can be found in egg yolks and liver.
Vitamin D works with calcium to increase bone strength and harden the bones. It works to increase active transport of calcium out of the osteoblasts into the extra-cellular fluid and in the kidneys. Vitamin D contributes to normal absorption and utilisation of calcium and phosphorus and maintenance of normal blood calcium concentrations. Vitamin D contributes to the maintenance of normal bones and teeth. It contributes to normal cell division and to the normal function of the immune system and healthy inflammatory response. Vitamin D also contributes to the maintenance of normal muscle function.
Boron is a mineral found at high levels in plant foods such as dried fruits, nuts, dark green leafy vegetables, applesauce, grape juice and cooked dried beans and peas. Boron is found in most tissues, but mainly in the bone, spleen and thyroid.
Potassium is an electrolyte stored in the muscles. Foods rich in potassium include bananas, oranges, cantaloupe, avocado, raw spinach, cabbage and celery. Potassium is an essential macromineral that helps maintain fluid balance in the body. It also plays a role in a wide variety of biochemical and physiological processes.
- Abbott L, Nadler J, Rude RK. Magnesium deficiency in alcoholism: possible contribution to osteoporosis and cardiovascular disease in alcoholics. Alcohol Clin Exp Res. 1994; 18:1076-1082.
- Altura BM, Altura BT. Role of magnesium and calcium in alcohol-induced hypertension and strokes as probed by in vivo television microscopy, digital image microscopy, optical spectroscopy, 31P-NMR, spectroscopy and a unique magnesium ion-selective electrode. Alcohol Clin Exp Res. 1994; 18:1057-1068.
- Baly DL, Schneiderman JS, Garcia-Welsh AL. Effect of manganese deficiency on insulin binding, glucose transport and metabolism in rat adipocytes. J Nutr. 1990; 120:1075-1079.
- Baron JA, Beach M, Mandel JS, et al. Calcium supplements for the prevention of colorectal adenomas. N Engl J Med 1999;340:101-107.
- Baron JA, Tosteson TD, Wargovich MJ, et al. Calcium supplementation and rectal mucosal proliferation: a randomized controlled trial. J Natl Cancer Inst 1995;87:1303-1307.
- Baxter GF, Sumeray MS, Walker JM. Infant size and magnesium: insights into LIMIT-2 and ISIS-4 from experimental studies. Lancet. 1996; 348:1424-1426.
- Beattie JH, Peace HS. The influence of a low-boron diet and boron supplementation on bone, major mineral and sex steroid metabolism in postmenopausal women. Br J Nutr. 1993 May;69(3):871-84.
- Bell L, Halstenson CE, Halstenson CJ, et al. Cholesterol-lowering effects of calcium carbonate in patients with mild to moderate hypercholesterolemia. Arch Intern Med. 1992; 152:2441-2444.
- Bostick RM, Kushi LH, Wu Y, et al. Relation of calcium, vitamin D, and dairy food intake to ischemic heart disease mortality among postmenopausal women. Am J Epidemiol 1999;149:151-160.
- Britton J, Pavord I, Richards K, et al. Dietary magnesium, lung function, wheezing, and airway hyper-reactivity in a random adult population sample. Lancet. 1994; 344:357-362.
- Buckley LM, Leib ES, Cartularo KS, et al. Calcium and vitamin D3 supplementation prevents bone loss in the spine secondary to low-dose corticosteroids in patients with rheumatoid arthritis. Ann Intern Med. 1996; 125:961-968.
- Casscells W. Magnesium and myocardial infarction. Lancet. 1994; 343:807-809.
- Christin Marandino, Vegetarian Times, August 1998
- Curhan GC, Willett WC, Speizer FE, et al. Comparison of dietary calcium with supplemental calcium and other nutrients as factors affecting the risk of kidney stones in women. Ann Intern Med. 1997; 126:497-504.
- Dawson-Hughes B, Harris SS, Krall EA, Dallal GE. Effect of calcium and vitamin D supplementation on bone density on men and women 65 years of age and older. N Engl J Med. 1997; 337:670-676.
- de Lourdes Lima M, Cruz T, Carreiro Pousada J, et al. The effect of magnesium supplementation in increasing doses on the control of type 2 diabetes. Diabetes Care. 1998; 21:682-686.
- Elisaf M, Merkouropoulos M, Tsianos EV. Siamopoulos KC. Pathogenetic mechanisms of hypomagnesemia in alcoholic patients. J Trace Elem Med Biol. 1995; 9:210-214.
- Facchinetti F, Borella P, Sances G, et al. Oral magnesium successfully relieves premenstrual mood changes. Obstet Gynecol. 1991; 78:177-181.
- Garland CF, Garland FC, Gorham ED. Calcium and vitamin D. Their potential roles in colon and breast cancer prevention. Ann NY Acad Sci. 1999; 889:107-119.
- Gong H, Amemiya T. Optic nerve changes in manganese-deficient rats. Exp Eye Res. 1999; 68:313-320.
- Gullestad L, Dolva LO, Soyland E, et al. Oral magnesium supplementation improves metabolic variables and muscle strength in alcoholics. Alcohol Clin Exp Res. 1992; 16:986-990.
- Health & Medicine. (Statistical Data Included) American Fitness, July, 1999 Tannen RL. Effects of potassium on blood pressure control. Ann Intern Med. 1983; 98(part 2):773-780.
- Heaney RP. Calcium, dairy products and osteoporosis. J Am Coll Nutr. 2000; 19(2 Suppl):83S-99S.
- Hussain S, Ali SF. Manganese scavenges superoxide and hydroxyl radicals: an in vitro study in rats. Neuroscience Letters. 1999; 261:21-24.
- ISIS-4 (Fourth International Study of Infarct Survival) Collaborative Group. ISIS-4: a randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulfate in 58,050 patients with suspected acute myocardial infarction. Lancet. 1995; 345:669-685.
- Jorde R, Sundsfjord J, Haug E, et al. Relation between low calcium intake, parathyroid hormone, and blood pressure. Hypertension 2000;35:1154-1159.
- Kao WHL, Folsom AR, Nieto J, et al. Serum and dietary magnesium and the risk for type 2 diabetes mellitus (editorial). Arch. Int Med. 1999; 159:2151-2159.
- Keen CL, Ensunsa JL, Watson MH, et al. Nutritional aspects of manganese from experimental studies. Neurotoxicol. 1999; 20:213-223.
- Krieger D, Krieger S, Jansen O, et al. Manganese and chronic hepatic encephalopathy. Lancet. 1995; 346:270-274.
- Lim R, Herzog WR. Magnesium for cardiac patients: is it a valuable treatment supplement? Contemp Int Med. 1998; 10:6-9.
- Lipkin M, Newmark H. Effect of added dietary calcium on colonic epithelial-cell proliferation in subjects at high risk for familial colonic cancer. N Engl J Med. 1985; 313:1381-1384.
- Lucas MJ, Leveno KJ, Cunningham FG. A comparison of magnesium sulfate with phenytoin for the prevention of eclampsia. N Engl J Med. 1995; 333:201-205.
- Martini LA. Magnesium supplementation and bone turnover. Nutr Rev. 1999; 57:227-229.
- Mauskop A, Altura BM. Role of magnesium in the pathogenesis and treatment of migraines. Clin Neurosci. 1998; 5:24-27.
- Naghii MR, Wall PM, Samman S. The boron content of selected foods and the estimation of its daily intake among free-living subjects. J Am Coll Nutr. 1996 Dec;15(6):614-9.
- Newnham RE. Essentiality of boron for healthy bones and joints. Environ Health Perspect. 1994;102:83-85
- Nielsen FH. Studies on the relationship between boron and magnesium which possibly affects the formation and maintenance of bones. Magnes Trace Elem. 1990;9:61-69
- Nielsen FH. Ultratrace minerals. In: Shils ME, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease, 9th ed. Baltimore, MD: Williams and Wilkins; 1999:283-303.
- Oginni LM, Sharp CA, Worsfold M, et al. Healing of rickets after calcium supplementation. Lancet. 1999; 353:296-297.
- Orchard TJ. Magnesium and type 2 diabetes mellitus (editorial). Arch Int Med. 1999; 159:2119-2120.
- Paolisso G, Sgamabato S, Pizza G, et al. Improved insulin response and action by chronic magnesium administration in aged NIDDM. Diabetes Care. 1989; 12:265-269.
- Peikert A, Wilimzig C, Kohne-Volland R. Prophylaxis of migraine with oral magnesium: results from a prospective, multi-center, placebo-controlled and double-blind randomized study. Cephalalgia. 1996; 16:257-263.
- Penland J.G. The importance of boron nutrition for brain and psychological function. Biol Trace Elem Res. 1998; 66:299-317.
- Recker RR. Calcium absorption and achlorhydria. N Engl J Med. 1985; 313:70-73. Reid IR, Ames RW, Evans MC, et al. Effect of calcium supplementation on bone loss in postmenopausal women. N Engl J Med. 1993; 328:460-464.
- Rivlin RS. Magnesium deficiency and alcohol intake: mechanisms, clinical significance and possible relation to cancer development (a review). J Am Coll Nutr. 1994; 13:416-423.
- Roberts JM. Magnesium for preeclampsia and eclampsia. N Engl J Med. 1995; 333:250-251.
- Roffe C, Fletcher S, Woods KL. Investigation of the effects of intravenous magnesium sulphate on cardiac rhythm in acute myocardial infarction. Br Heart J. 1994; 71:141-145.
- Saris N-EL, Mervaala E, Karppanen H, et al. Magnesium. An update on physiological, clinical and analytical aspects (review). Clinica Chimica Acta. 2000; 294:1-26.
- Shils ME. Magnesium. In: Shils M, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease. 9th ed. Baltimore, MD: Williams and Wilkins; 1999:169-192.
- Singh MA. Combined exercise and dietary intervention to optimize body composition in aging. Ann N Y Acad Sci. 1998 Nov 20;854:378-93.
- Singh N, Singh PN, Hershman JM. Effect of calcium carbonate on the absorption of levothyroxine. JAMA. 2000; 283:2822-2825.
- Sojka JE. Magnesium supplementation and osteoporosis. Nutr Rev. 1995; 53:71-80.
- Strause L, Saltman P, Glowacki J. The effect of deficiencies of manganese and copper on osteo-induction and on resorption of bone particles in rats. Calcif Tissue Int. 1987; 41:145-150
- Strause L, Saltman P, Smith KT, et al. Spinal bone loss in postmenopausal women supplemented with calcium and trace minerals. J Nutr. 1994; 124:1060-1064.
- Sutherland B, Strong P, King JC. Determining human dietary requirements for boron. Biol Trace Elem Res. 1998 Winter;66(1-3):193-204.
- Talbot JR, Guardo P, Seccia S, et al. Calcium bioavailability and parathyroid hormone acute changes after oral intake of dairy and nondairy products in healthy volunteers. Osteoporosis Int. 1999; 10:137-142.
- Tobian L. Salt and hypertension. Lessons from animal models that relate to human hypertension. Hypertension. 1991; 17:152-158.
- Tosiello L. Hypomagnesemia and diabetes mellitus. A review of clinical implications. Arch Intern Med. 1998; 156:1143-1148.
- Volpe SL, Taper LJ, Meacham S. The relationship between boron and magnesium status and bone mineral density in the human: a review. Magnes Res. 1993;6:291-296
- Wargovich MJ, Eng VWS, Newmark HL. Calcium inhibits the damaging and compensatory proliferative effects of fatty acids on mouse colon epithelium. Cancer Lett. 1984; 23:253-258.
- Weaver CM, Heaney RP. Calcium. In: Shils ME, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease. 9th ed. Baltimore, MD: Williams and Wilkins; 1999:141-155.
- Wolf RL, Cauley JA, Baker CE, et al. Factors associated with calcium absorption efficiency in pre- and perimenopausal women. Am J Clin Nutr. 2000; 72:466-471.
- Woods KL, Fletcher S. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2). Lancet. 1994; 343:816-819.
- Zemel MB, Shi H, Greer B, et al. Regulation of adiposity by dietary calcium. FASEB J. 2000; 14:1132-1138.
- Allender PS, Cutler JA, Follman D, et al. Dietary calcium and blood pressure: meta—analysis of randomized clinical trials. Ann Intern Med. 1996; 124:825-831.
- Christiansen CW, Rieder MA, Silverstein EL, Gencheff NE. Magnesium sulfate reduces myocardial infarct size when administered before but not after coronary reperfusion in a canine model. Circulation. 1995; 92:2617-2621.
- Dietary Reference Intakes for Calcium, Phosphorous, Magnesium, Vitamin D, and Fluoride. Washington, DC: National Academy Press; 1997.
- Durlach J, Durlach V, Bac P, et al. Magnesium and therapeutics. Magnes Res. 1994; 7:313-328.
Why should I take calcium?
Everyone needs calcium. Practically no one ingests enough calcium in their daily diet. Besides being helpful in supporting and maintaining bone integrity, calcium serves a dynamic role as a mineral. It's very important in the activity of many bodily enzymes and maintaining proper fluid balance. Calcium aids in the contraction of skeletal and muscle.
I'm not an elderly woman; why should I take a calcium supplement?
Calcium plays a huge role in regulating many major bodily processes with implications that extend far beyond the age factor. Other than elderly women who may be susceptible to bone loss, younger women, pregnant and breastfeeding women, growing children and men should take a calcium supplement.
Younger women need more calcium to build up the strength of their bones. Pregnant and breastfeeding women need extra calcium to foster the healthy growth of new cells and of breast milk. Those with poor cardiovascular health have been found to have low levels of calcium intake. Studies have confirmed the positive impact of calcium supplementation on heart health.
Why is Isotonix Calcium Plus better than other calcium products?
It is better because of the Isotonix delivery system. The secret of the isotonic process is probably now becoming clear! When an isotonic substance enters the body, it will be absorbed into the bloodstream rapidly. With isotonic fluids, little nutritive value is lost making the absorption of nutrients highly efficient. There is nothing artificial about it. An isotonic fluid is nature's own nutrient delivery system.
Why is there a sandy residue left in the cup after mixing with water?
Everyone's water is different; some tap water has a higher concentration of minerals and the pH level of water differs depending on geographic location and the quality of the tap water, which can lead to inconsistencies with the saturation point of a solution. To ensure that our solutions reach the point of saturation, regardless of the pH or mineral levels in water, we have maximised the formulation amounts so that every serving of Isotonix Calcium Plus contains the correct amount of calcium. The residue left in the cup is due to over-saturation which is common in tap water with a higher pH level or a higher mineral content.
What form of Calcium should I take?
The best form of calcium is calcium carbonate which is utilised by the body more efficiently, due to the fact that it increases the absorbability. Additionally, calcium is more readily absorbed by the body when in combination with magnesium, manganese, vitamin C, vitamin B2, boron and potassium. Isotonix Calcium Plus is formulated with calcium carbonate and the additional vitamins and minerals needed in an isotonic form which allows for maximum utilisation and absorption of calcium by the body and reduces the nutritive loss found in many calcium tablets or capsules.